ExoticRx · exoticrx.com/drugs/adapalene
Adapalene
Differin
Drug Class
Routes
Indications
Mechanism of Action
Third-generation retinoid selectively binding RAR-beta and RAR-gamma nuclear receptors. Normalizes follicular keratinization and has anti-inflammatory activity.
Side effects & warnings
Limited veterinary use. Investigated for chin acne (feline) and comedone syndromes. Local irritation expected initially. Teratogenic. Photosensitization.
Species with Adapalene dosing data (1 dose rule)
Evidence levels across 1 dose rule
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
Backed by a published primary source
- · BSAVA Small Animal Formulary, 10th Ed
Sample dosing (1 of 1 cited rule)
Free-tier preview — dog and cat dosing. Pro and Student unlock all 1 species including reptiles, birds, pocket pets, livestock, and equine.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | Topical | 0 mg/kg | q24h | Weak | BSAVA Small Animal Formulary, 10th Ed |
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Source citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.