ExoticRx · exoticrx.com/drugs/griseofulvin
Fulvicin, Grisovin
Inhibits fungal mitosis by disrupting mitotic spindle microtubules. Deposits in keratin precursor cells, preventing fungal invasion of new growth.
TERATOGENIC — CONTRAINDICATED in pregnant animals. Bone marrow suppression (especially cats — monitor CBC). Give with fatty food (enhances absorption). Cats: FIV-positive at higher risk of toxicity. 4-8 week course minimum.
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Free-tier preview — dog and cat dosing. Pro and Student unlock all 2 species including reptiles, birds, pocket pets, livestock, and equine.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | PO | 25–50 mg/kg | q12-24h | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed |
| Cat (Domestic) | PO | 25–50 mg/kg | q12-24h | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed |
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