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Flucytosine Topical

Ancotil Cream

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Sourced from primary literature. Awaiting credentialed clinical reviewer — our editorial process.

Drug Class

Antifungal

Routes

Topical

Indications

Cutaneous fungal infectionsCutaneous yeast infections (adjunct)

Mechanism of Action

Converted to 5-fluorouracil by fungal cytosine deaminase, inhibiting thymidylate synthase and RNA/DNA synthesis.

Side effects & warnings

Topical formulation for cutaneous fungal infections. Less toxic than systemic form. Resistance develops quickly — combine with other antifungals.

Species with Flucytosine Topical dosing data (2 dose rules)

Evidence levels across 2 dose rules

Weak×2

Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.

Backed by a published primary source

  • · Plumb's Veterinary Drug Handbook, 9th Ed

Sample dosing (2 of 2 cited rules)

Free-tier preview — dog and cat dosing. Pro and Student unlock all 2 species including reptiles, birds, pocket pets, livestock, and equine.

SpeciesRouteDoseFrequencyEvidenceSource
Dog (Domestic)Topical0 apply thin layerq12hWeakPlumb's Veterinary Drug Handbook, 9th Ed
Cat (Domestic)Topical0 apply thin layerq12hWeakPlumb's Veterinary Drug Handbook, 9th Ed

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Other formulations of Flucytosine