Question 1

What is Edrophonium used for?

Accepted Answer

Edrophonium is indicated for: Myasthenia gravis (diagnostic Tensilon test), Myasthenia gravis (diagnostic).

Question 2

What routes can Edrophonium be administered by?

Accepted Answer

Available routes: IV.

Question 3

Which species have cited Edrophonium dosing data?

Accepted Answer

Edrophonium dosing in the ExoticRx formulary covers 2 species: Cat (Domestic), Dog (Domestic).

Question 4

Is Edrophonium a controlled substance?

Accepted Answer

Edrophonium is not federally scheduled as a controlled substance, but is veterinary prescription only in most jurisdictions.

Question 5

What are the warnings or contraindications for Edrophonium?

Accepted Answer

Very short duration (5-10 minutes). Have atropine ready for cholinergic reactions. False negatives possible. Use IV only with monitoring.

Question 6

What are the side effects of Edrophonium?

Accepted Answer

Very short duration (5-10 minutes). Have atropine ready for cholinergic reactions. False negatives possible. Use IV only with monitoring.

Question 7

How does Edrophonium work?

Accepted Answer

Ultra-short-acting reversible acetylcholinesterase inhibitor used diagnostically. Transient improvement in myasthenia gravis confirms the diagnosis.

Species	Route	Dose	Frequency	Evidence	Source
Dog (Domestic)	IV	0.1–0.2 mg/kg	Single IV test dose	Strong	Plumb's Veterinary Drug Handbook, 9th Ed; ACVIM Consensus on MG
Cat (Domestic)	IV	0.1–0.2 mg/kg	Single IV test dose	Moderate	Plumb's Veterinary Drug Handbook, 9th Ed

Edrophonium

Drug Class