ExoticRx · exoticrx.com/drugs/echothiophate-iodide-ophthalmic
Phospholine Iodide
Irreversible acetylcholinesterase inhibitor that produces prolonged miosis and increased aqueous outflow through the trabecular meshwork.
Long-acting — irreversible inhibition. Systemic cholinergic effects possible (bradycardia, GI hypermotility). Contraindicated with depolarizing neuromuscular blockers. Used for glaucoma refractory to other miotics.
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
Free-tier preview — dog and cat dosing. Pro and Student unlock all 1 species including reptiles, birds, pocket pets, livestock, and equine.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | Ophthalmic | 0 mg/kg | 1 drop affected eye q12h-q24h | Moderate | Gelatt KN, Veterinary Ophthalmology, 6th Ed |
| Dog (Domestic) | Ophthalmic | 0 mg/kg | 1 drop each eye q24h for diagnostic trial | Weak | Gelatt KN, Veterinary Ophthalmology, 6th Ed |
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