ExoticRx · exoticrx.com/drugs/dorzolamide-timolol-ophthalmic
Cosopt
Dorzolamide inhibits carbonic anhydrase in ciliary body, reducing aqueous humor production. Timolol is a beta-blocker reducing aqueous production via different mechanism. Additive IOP-lowering.
Contraindicated with systemic beta-blockers (additive bradycardia). Avoid in cats with asthma. Local stinging common. Monitor IOP response.
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
Free-tier preview — dog and cat dosing. Pro and Student unlock all 2 species including reptiles, birds, pocket pets, livestock, and equine.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | TOPICAL (ophthalmic) | 0 1 drop per eye | q8-12h | Strong | Plumb's Veterinary Drug Handbook, 9th Ed |
| Cat (Domestic) | TOPICAL (ophthalmic) | 0 1 drop per eye | q8-12h | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed |
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