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Dinoprost Tromethamine (Livestock)

Lutalyse, ProstaMate

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Sourced from primary literature. Awaiting credentialed clinical reviewer — our editorial process.

Drug Class

Endocrine

Routes

IM

Indications

abortionendometritis treatmentEstrus synchronizationInduction of parturitionLuteolysisParturition inductionpyometrasynchronization

Mechanism of Action

Natural prostaglandin F2-alpha that causes luteolysis (regression of the corpus luteum), resulting in a decline in progesterone and return to estrus. Also causes uterine contraction and cervical relaxation.

Side effects & warnings

Do not handle if pregnant or have asthma — absorbed through skin and may cause bronchospasm or abortion. Wear protective gloves. Transient side effects include sweating, increased respiration, and mild colic in mares.

Species with Dinoprost Tromethamine (Livestock) dosing data (6 dose rules)

Cattle (Beef/Dairy)Horse (Equine)Swine (Pig)

Evidence levels across 6 dose rules

Strong×6

Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.

Backed by 2 published primary sources

  • · FDA NADA Label
  • · Plumb's Veterinary Drug Handbook, 9th Ed

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Calculate Dosage for Dinoprost Tromethamine (Livestock)