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Dinoprost Tromethamine (Livestock) for Cattle

Dinoprost Tromethamine (Livestock) is used in cattle for abortion, endometritis treatment, Estrus synchronization, Induction of parturition. Routes documented in cattle: IM. ExoticRx tracks Dinoprost Tromethamine (Livestock) dosing for cattle from primary veterinary literature; sign in to view the full rule set. Verify against current literature before clinical use.

Trade names: Lutalyse, ProstaMate

Dose rules — sign in to view

Cited dose rules for Dinoprost Tromethamine (Livestock) in cattle are available with a free ExoticRx account. Each row carries the route, dose range, frequency, indication, evidence level, and primary-source citation.

Sources include: FDA NADA Label; Plumb's Veterinary Drug Handbook, 9th Ed

Mechanism of action

Natural prostaglandin F2-alpha that causes luteolysis (regression of the corpus luteum), resulting in a decline in progesterone and return to estrus. Also causes uterine contraction and cervical relaxation.

Side effects & warnings

Do not handle if pregnant or have asthma — absorbed through skin and may cause bronchospasm or abortion. Wear protective gloves. Transient side effects include sweating, increased respiration, and mild colic in mares.

Species-specific contraindications and adverse-reaction reports for cattle may differ from canine / feline reference data — consult the primary citations listed with each rule.

Why a species-specific page? Dinoprost Tromethamine (Livestock) pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cattle — the rules above are the citations specific to this species, not generic recommendations.

Sourced from primary literature; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.