Dinoprost Tromethamine (Livestock) for Swine
Dinoprost Tromethamine (Livestock) is used in swine for abortion, endometritis treatment, Estrus synchronization, Induction of parturition. Routes documented in swine: IM. ExoticRx tracks Dinoprost Tromethamine (Livestock) dosing for swine from primary veterinary literature; sign in to view the full rule set. Verify against current literature before clinical use.
Trade names: Lutalyse, ProstaMate
Dose rules — sign in to view
Cited dose rules for Dinoprost Tromethamine (Livestock) in swine are available with a free ExoticRx account. Each row carries the route, dose range, frequency, indication, evidence level, and primary-source citation.
Mechanism of action
Natural prostaglandin F2-alpha that causes luteolysis (regression of the corpus luteum), resulting in a decline in progesterone and return to estrus. Also causes uterine contraction and cervical relaxation.
Side effects & warnings
Do not handle if pregnant or have asthma — absorbed through skin and may cause bronchospasm or abortion. Wear protective gloves. Transient side effects include sweating, increased respiration, and mild colic in mares.
Species-specific contraindications and adverse-reaction reports for swine may differ from canine / feline reference data — consult the primary citations listed with each rule.
Why a species-specific page? Dinoprost Tromethamine (Livestock) pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in swine — the rules above are the citations specific to this species, not generic recommendations.
Sourced from primary literature; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.