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Derquantel for Sheep

Derquantel is used in sheep for GI nematodes (combined, Nematode infections (investigational). Routes documented in sheep: PO. ExoticRx tracks Derquantel dosing for sheep from primary veterinary literature; sign in to view the full rule set. Verify against current literature before clinical use.

Trade names: Startect

Dose rules — sign in to view

Cited dose rules for Derquantel in sheep are available with a free ExoticRx account. Each row carries the route, dose range, frequency, indication, evidence level, and primary-source citation.

Sources include: Merck Veterinary Manual; Papich Handbook of Veterinary Drugs, 5th Ed

Mechanism of action

Antagonist at nicotinic acetylcholine receptors in nematodes, causing flaccid paralysis. Novel mechanism complements macrocyclic lactone activity.

Side effects & warnings

Combined with abamectin for broader spectrum. Primarily for livestock. Limited companion animal data. Generally well tolerated.

Species-specific contraindications and adverse-reaction reports for sheep may differ from canine / feline reference data — consult the primary citations listed with each rule.

Why a species-specific page? Derquantel pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in sheep — the rules above are the citations specific to this species, not generic recommendations.

Sourced from primary literature; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.