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Derquantel

Startect(combination)

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Sourced from primary literature. Awaiting credentialed clinical reviewer — our editorial process.

Drug Class

Antiparasitic

Routes

PO

Indications

GI nematodes (combinedNematode infections (investigational)

Mechanism of Action

Antagonist at nicotinic acetylcholine receptors in nematodes, causing flaccid paralysis. Novel mechanism complements macrocyclic lactone activity.

Side effects & warnings

Combined with abamectin for broader spectrum. Primarily for livestock. Limited companion animal data. Generally well tolerated.

Species with Derquantel dosing data (3 dose rules)

Cat (Domestic)Dog (Domestic)Sheep (Ovine)

Evidence levels across 3 dose rules

Extrapolated×2Strong×1

Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.

Backed by 2 published primary sources

  • · Merck Veterinary Manual
  • · Papich Handbook of Veterinary Drugs, 5th Ed

Sample dosing (2 of 3 cited rules)

Free-tier preview — dog and cat dosing. Pro and Student unlock all 3 species including reptiles, birds, pocket pets, livestock, and equine.

SpeciesRouteDoseFrequencyEvidenceSource
Dog (Domestic)PO1–2 mg/kgSingle doseExtrapolatedPapich Handbook of Veterinary Drugs, 5th Ed
Cat (Domestic)PO1–2 mg/kgSingle doseExtrapolatedPapich Handbook of Veterinary Drugs, 5th Ed

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