ExoticRx · exoticrx.com/drugs/cyclosporine-ophthalmic-0-05
Restasis, Optimmune, Ciclosporin Ophthalmic
Calcineurin inhibitor that suppresses T-cell mediated inflammation in the lacrimal gland. Increases tear production by reducing immune-mediated destruction of lacrimal tissue.
Standard of care for canine keratoconjunctivitis sicca. May take 4-6 weeks for full effect. Transient stinging on application. Also available as 0.2% veterinary formulation (Optimmune).
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| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | Ophthalmic | 0 mg/kg | 1 drop affected eye(s) q12h | Strong | Gelatt KN, Veterinary Ophthalmology, 6th Ed |
| Dog (Domestic) | Ophthalmic | 0 mg/kg | q12h | Strong | Plumb's Veterinary Drug Handbook, 9th Ed |
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