ExoticRx · exoticrx.com/drugs/topiramate
Topamax
Multiple mechanisms: blocks voltage-gated sodium channels, enhances GABA-A activity, antagonizes AMPA/kainate glutamate receptors, inhibits carbonic anhydrase.
Used as adjunctive anticonvulsant. Sedation, ataxia. Metabolic acidosis (carbonic anhydrase inhibition). Weight loss. Renal stones. Limited veterinary data.
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
Free-tier preview — dog and cat dosing. Pro and Student unlock all 1 species including reptiles, birds, pocket pets, livestock, and equine.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | PO | 2–10 mg/kg | q8-12h | Weak | Plumb's Veterinary Drug Handbook, 9th Ed |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.