Question 1

What is Tobramycin Systemic used for?

Accepted Answer

Tobramycin Systemic is indicated for: Serious gram-negative infections, Serious Pseudomonas and gram-negative infections.

Question 2

What routes can Tobramycin Systemic be administered by?

Accepted Answer

Available routes: IV, IM.

Question 3

Which species have cited Tobramycin Systemic dosing data?

Accepted Answer

Tobramycin Systemic dosing in the ExoticRx formulary covers 2 species: Cat (Domestic), Dog (Domestic).

Question 4

Is Tobramycin Systemic a controlled substance?

Accepted Answer

Tobramycin Systemic is not federally scheduled as a controlled substance, but is veterinary prescription only in most jurisdictions.

Question 5

What are the warnings or contraindications for Tobramycin Systemic?

Accepted Answer

Nephrotoxic and ototoxic. Therapeutic drug monitoring essential. Avoid concurrent nephrotoxins. Ensure adequate hydration.

Question 6

What are the side effects of Tobramycin Systemic?

Accepted Answer

Nephrotoxic and ototoxic. Therapeutic drug monitoring essential. Avoid concurrent nephrotoxins. Ensure adequate hydration.

Question 7

How does Tobramycin Systemic work?

Accepted Answer

Binds 30S ribosomal subunit causing misreading of mRNA. Bactericidal. Particularly effective against Pseudomonas aeruginosa.

Species	Route	Dose	Frequency	Evidence	Source
Dog (Domestic)	IV	2–4 mg/kg	q8h or 6-10 mg/kg q24h	Moderate	Plumb's Veterinary Drug Handbook, 9th Ed
Cat (Domestic)	IV	2–3 mg/kg	q8h or 5-8 mg/kg q24h	Moderate	Plumb's Veterinary Drug Handbook, 9th Ed

Tobramycin Systemic

Drug Class