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Ampicillin

Polyflex

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Sourced from primary literature. Awaiting credentialed clinical reviewer — our editorial process.

Drug Class

Antibiotic

Routes

POIVIMSC

Indications

bacteremiaBacterial infectionerysipelaslisteriosisRespiratoryRespiratory infectionssoft tissue infectionsSurgical prophylaxisSusceptible bacterial infections

Mechanism of Action

Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins. Broader spectrum than penicillin G with gram-negative coverage.

Side effects & warnings

CONTRAINDICATED in rabbits, guinea pigs, and hamsters (fatal dysbiosis). May cause GI upset. Cross-reactivity with other beta-lactams. IM injection may be painful.

Species with Ampicillin dosing data (9 dose rules)

Evidence levels across 9 dose rules

Strong×4Moderate×5

Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.

Backed by 3 published primary sources

  • · Carpenter's Exotic Animal Formulary, 6th Ed
  • · Plumb's Veterinary Drug Handbook
  • · Plumb's Veterinary Drug Handbook, 9th Ed

Sample dosing (2 of 9 cited rules)

Free-tier preview — dog and cat dosing. Pro and Student unlock all 6 species including reptiles, birds, pocket pets, livestock, and equine.

SpeciesRouteDoseFrequencyEvidenceSource
Dog (Domestic)IV20–40 mg/kgq6-8hStrongPlumb's Veterinary Drug Handbook, 9th Ed
Dog (Domestic)PO10–20 mg/kgq6-8hStrongPlumb's Veterinary Drug Handbook, 9th Ed

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