ExoticRx · exoticrx.com/drugs/thiamylal
Bio-Tal, Surital
Ultra-short-acting thiobarbiturate that enhances GABA-A receptor activity, producing rapid-onset general anesthesia. Highly lipophilic with redistribution-dependent recovery.
Perivascular injection causes severe tissue necrosis. Respiratory depression and apnea common. Sighthounds (greyhounds) have prolonged recovery due to low body fat. Largely replaced by propofol.
Controlled substance
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| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | IV | 8–18 mg/kg | Single dose (induction) | Strong | Plumb's Veterinary Drug Handbook, 9th Ed; FDA openFDA Adverse Event Database |
| Cat (Domestic) | IV | 8–15 mg/kg | Single dose (induction) | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed; FDA openFDA Adverse Event Database |
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