ExoticRx · exoticrx.com/drugs/sevoflurane
SevoFlo, Sevofrane
Enhances GABA-A and glycine receptor activity while inhibiting NMDA receptors and nicotinic acetylcholine receptors. Produces dose-dependent anesthesia.
Requires precision vaporizer. Dose-dependent cardiovascular/respiratory depression. Rapid induction and recovery (low blood-gas solubility). Non-irritating to airways. Compound A production with soda lime (low flow caution).
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
Free-tier preview — dog and cat dosing. Pro and Student unlock all 2 species including reptiles, birds, pocket pets, livestock, and equine.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | INHALATION | 2–3.5 % (MAC 2.4%) | Continuous | Strong | Plumb's Veterinary Drug Handbook, 9th Ed |
| Cat (Domestic) | INHALATION | 2.5–4 % (MAC 2.6%) | Continuous | Strong | Plumb's Veterinary Drug Handbook, 9th Ed |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.