Question 1

What is Selamectin used for?

Accepted Answer

Selamectin is indicated for: Caparinia mites (first-line), ear mites, External parasites, fleas, fur mites (Cheyletiella), Heartworm prevention, intestinal parasites, sarcoptic mange.

Question 2

What routes can Selamectin be administered by?

Accepted Answer

Available routes: TOPICAL.

Question 3

Which species have cited Selamectin dosing data?

Accepted Answer

Selamectin dosing in the ExoticRx formulary covers 7 species: African Pygmy Hedgehog, Cat (Domestic), Chinchilla, Dog (Domestic), Ferret, Pet Rat, Rabbit (Domestic).

Question 4

Is Selamectin a controlled substance?

Accepted Answer

Selamectin is not federally scheduled as a controlled substance, but is veterinary prescription only in most jurisdictions.

Question 5

What are the warnings or contraindications for Selamectin?

Accepted Answer

Do not apply to broken skin. Monthly application. Prevents heartworm, kills fleas, treats ear mites, sarcoptic mange. Safe in MDR1 dogs at labeled dose. OK in rabbits and ferrets.

Question 6

What are the side effects of Selamectin?

Accepted Answer

Do not apply to broken skin. Monthly application. Prevents heartworm, kills fleas, treats ear mites, sarcoptic mange. Safe in MDR1 dogs at labeled dose. OK in rabbits and ferrets.

Question 7

How does Selamectin work?

Accepted Answer

Binds glutamate-gated chloride channels in invertebrate nerve/muscle cells. Absorbed through skin; reaches systemic circulation.

Species	Route	Dose	Frequency	Evidence	Source
Dog (Domestic)	TOPICAL	6–12 mg/kg	q30d	Strong	Plumb's Veterinary Drug Handbook, 9th Ed
Cat (Domestic)	TOPICAL	6–12 mg/kg	q30d	Strong	Plumb's Veterinary Drug Handbook, 9th Ed

Selamectin

Drug Class

Routes

Indications

Mechanism of Action

Side effects & warnings

Species with Selamectin dosing data (7 dose rules)

Evidence levels across 7 dose rules

Backed by 6 published primary sources

Sample dosing (2 of 7 cited rules)

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