ExoticRx · exoticrx.com/drugs/piperacillin-tazobactam
Zosyn
Piperacillin inhibits cell wall synthesis; tazobactam inhibits many beta-lactamases restoring activity against resistant organisms.
Adjust dose for renal impairment. Monitor bleeding (platelet dysfunction). GI upset. Sodium content may be significant in fluid-restricted patients.
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
Free-tier preview — dog and cat dosing. Pro and Student unlock all 2 species including reptiles, birds, pocket pets, livestock, and equine.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | IV | 50–100 mg/kg | q6-8h | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed |
| Cat (Domestic) | IV | 50–100 mg/kg | q6-8h | Weak | Plumb's Veterinary Drug Handbook, 9th Ed |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.