ExoticRx · exoticrx.com/drugs/phenylpiperazine-derivatives-trazodone-extended-release
Compounded ER Trazodone
Serotonin antagonist and reuptake inhibitor (SARI). Blocks 5-HT2A receptors and inhibits serotonin reuptake. Extended-release formulation provides longer anxiolysis.
Compounded ER formulation — do not crush. Sedation is primary effect. Serotonin syndrome risk with SSRIs. Priapism reported rarely. Dose to effect.
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
Free-tier preview — dog and cat dosing. Pro and Student unlock all 2 species including reptiles, birds, pocket pets, livestock, and equine.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | PO | 3–10 mg/kg | q12-24h | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed |
| Cat (Domestic) | PO | 2–5 mg/kg | q12-24h | Weak | Plumb's Veterinary Drug Handbook, 9th Ed |
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