Penicillin G for Sheep
Penicillin G is used in sheep for Bacterial infections, blackleg, foot rot, Gram-positive infections. Routes documented in sheep: IM, IV, SC. ExoticRx tracks Penicillin G dosing for sheep from primary veterinary literature; sign in to view the full rule set. Verify against current literature before clinical use.
Trade names: Pen-G, Crysticillin
Dose rules — sign in to view
Cited dose rules for Penicillin G in sheep are available with a free ExoticRx account. Each row carries the route, dose range, frequency, indication, evidence level, and primary-source citation.
Mechanism of action
Inhibits bacterial cell wall synthesis by binding PBPs. Bactericidal. Narrow spectrum: primarily gram-positive and some anaerobes.
Side effects & warnings
CONTRAINDICATED in rabbits, guinea pigs, hamsters. Hypersensitivity reactions. Procaine form: IM/SC only (never IV). Potassium form: slow IV only. Pain at injection site.
Species-specific contraindications and adverse-reaction reports for sheep may differ from canine / feline reference data — consult the primary citations listed with each rule.
Why a species-specific page? Penicillin G pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in sheep — the rules above are the citations specific to this species, not generic recommendations.
Sourced from primary literature; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.