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Ofloxacin Otic

Floxin Otic

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Sourced from primary literature. Awaiting credentialed clinical reviewer — our editorial process.

Drug Class

Otic

Routes

Otic

Indications

Otitis mediaOtitis media (Pasteurella)perforated tympanic membrane

Mechanism of Action

Fluoroquinolone antibiotic that inhibits bacterial DNA gyrase, preventing DNA replication. Broad-spectrum activity against gram-positive and gram-negative otic pathogens.

Side effects & warnings

Safe with perforated tympanic membrane — non-ototoxic. Solution formulation (not suspension) for better middle ear penetration. Good Pseudomonas activity.

Species with Ofloxacin Otic dosing data (2 dose rules)

Evidence levels across 2 dose rules

Strong×1Moderate×1

Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.

Backed by 2 published primary sources

  • · Carpenter's Exotic Animal Formulary, 6th Ed
  • · Miller WH, Small Animal Dermatology, 7th Ed

Sample dosing (1 of 2 cited rules)

Free-tier preview — dog and cat dosing. Pro and Student unlock all 2 species including reptiles, birds, pocket pets, livestock, and equine.

SpeciesRouteDoseFrequencyEvidenceSource
Dog (Domestic)Otic0 mg/kg5-10 drops affected ear q12hStrongMiller WH, Small Animal Dermatology, 7th Ed

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