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Ciprofloxacin-Dexamethasone Otic

Ciprodex

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Sourced from primary literature. Awaiting credentialed clinical reviewer — our editorial process.

Drug Class

Otic

Routes

Otic

Indications

Bacterial otitis externaPseudomonas otitis externa

Mechanism of Action

Ciprofloxacin inhibits bacterial DNA gyrase and topoisomerase IV. Dexamethasone suppresses inflammatory mediators. Combined for infected, inflamed ears.

Side effects & warnings

Good Pseudomonas coverage. Shake well before use. Avoid if tympanic membrane is perforated. 7-day typical treatment course.

Species with Ciprofloxacin-Dexamethasone Otic dosing data (2 dose rules)

Cat (Domestic)Dog (Domestic)

Evidence levels across 2 dose rules

Strong×1Moderate×1

Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.

Backed by a published primary source

  • · Miller WH, Small Animal Dermatology, 7th Ed

Sample dosing (2 of 2 cited rules)

Free-tier preview — dog and cat dosing. Pro and Student unlock all 2 species including reptiles, birds, pocket pets, livestock, and equine.

SpeciesRouteDoseFrequencyEvidenceSource
Dog (Domestic)Otic0 mg/kg5-10 drops affected ear q12hStrongMiller WH, Small Animal Dermatology, 7th Ed
Cat (Domestic)Otic0 mg/kg3-5 drops affected ear q12hModerateMiller WH, Small Animal Dermatology, 7th Ed

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Calculate Dosage for Ciprofloxacin-Dexamethasone Otic