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Novobiocin

Albamycin, component of Albaplex

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Sourced from primary literature. Awaiting credentialed clinical reviewer — our editorial process.

Drug Class

Antibiotic

Routes

PO

Indications

Staphylococcal infections (combination)

Mechanism of Action

Inhibits bacterial DNA gyrase B subunit, blocking ATPase activity. Active primarily against gram-positive bacteria especially staphylococci.

Side effects & warnings

Often used in combination. GI upset common. Hepatotoxicity reported. Resistance develops rapidly with monotherapy.

Species with Novobiocin dosing data (1 dose rule)

Evidence levels across 1 dose rule

Weak×1

Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.

Backed by a published primary source

  • · Plumb's Veterinary Drug Handbook, 9th Ed

Sample dosing (1 of 1 cited rule)

Free-tier preview — dog and cat dosing. Pro and Student unlock all 1 species including reptiles, birds, pocket pets, livestock, and equine.

SpeciesRouteDoseFrequencyEvidenceSource
Dog (Domestic)PO10–22 mg/kgq12hWeakPlumb's Veterinary Drug Handbook, 9th Ed

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