Question 1

What is Neomycin used for?

Accepted Answer

Neomycin is indicated for: Bacterial enteritis, Bacterial enteritis (E. coli scours), Hepatic encephalopathy, Hepatic encephalopathy (reduce ammonia).

Question 2

What routes can Neomycin be administered by?

Accepted Answer

Available routes: PO, TOPICAL.

Question 3

Which species have cited Neomycin dosing data?

Accepted Answer

Neomycin dosing in the ExoticRx formulary covers 4 species: Cat (Domestic), Cattle (Beef/Dairy), Dog (Domestic), Swine (Pig).

Question 4

Is Neomycin a controlled substance?

Accepted Answer

Neomycin is not federally scheduled as a controlled substance, but is veterinary prescription only in most jurisdictions.

Question 5

What are the warnings or contraindications for Neomycin?

Accepted Answer

Do NOT give parenterally (severe nephrotoxicity/ototoxicity). Oral use reduces ammonia-producing GI bacteria. Prolonged oral use may cause malabsorption.

Question 6

What are the side effects of Neomycin?

Accepted Answer

Do NOT give parenterally (severe nephrotoxicity/ototoxicity). Oral use reduces ammonia-producing GI bacteria. Prolonged oral use may cause malabsorption.

Question 7

How does Neomycin work?

Accepted Answer

Binds 30S ribosomal subunit, inhibiting protein synthesis. Poorly absorbed orally; used for GI decontamination or topically.

Species	Route	Dose	Frequency	Evidence	Source
Dog (Domestic)	PO	10–20 mg/kg	q6-12h	Moderate	Plumb's Veterinary Drug Handbook, 9th Ed
Cat (Domestic)	PO	10–20 mg/kg	q6-12h	Moderate	Plumb's Veterinary Drug Handbook, 9th Ed

Neomycin

Drug Class

Routes

Indications

Mechanism of Action

Side effects & warnings

Species with Neomycin dosing data (4 dose rules)

Evidence levels across 4 dose rules

Backed by 2 published primary sources

Sample dosing (2 of 4 cited rules)

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