ExoticRx · exoticrx.com/drugs/n-butylscopolammonium-bromide
Buscopan, Buscopan Compositum, Hyoscine
Quaternary ammonium anticholinergic that blocks muscarinic receptors on GI smooth muscle, reducing spasm and motility. Does not cross the blood-brain barrier, limiting central side effects.
Tachycardia is common and expected. Transient ileus possible. Contraindicated in mechanical GI obstruction. Used primarily in horses for colic. Monitor heart rate during administration.
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Free-tier preview — dog and cat dosing. Pro and Student unlock all 2 species including reptiles, birds, pocket pets, livestock, and equine.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | IV | 0.3–0.5 mg/kg | q8-12h | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed; FDA openFDA Adverse Event Database |
| Cat (Domestic) | IV | 0.3–0.5 mg/kg | q8-12h | Extrapolated | Plumb's Veterinary Drug Handbook, 9th Ed; FDA openFDA Adverse Event Database |
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