ExoticRx · exoticrx.com/drugs/alosetron
Lotronex
Selective serotonin 5-HT3 receptor antagonist that inhibits visceral afferent activity, reducing colonic motility and secretion.
Risk of ischemic colitis and severe constipation. Very restricted use in human medicine. Minimal veterinary data — investigational only.
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
Free-tier preview — dog and cat dosing. Pro and Student unlock all 2 species including reptiles, birds, pocket pets, livestock, and equine.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | PO | 0.01–0.05 mg/kg | q12h | Weak | Veterinary Gastroenterology Literature Review |
| Cat (Domestic) | PO | 0.01–0.04 mg/kg | q12h | Extrapolated | Veterinary Gastroenterology Literature Review |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.