Question 1

What is Mupirocin used for?

Accepted Answer

Mupirocin is indicated for: MRSA/MRSP superficial skin infections, MRSP, Superficial pyoderma, Superficial skin infections.

Question 2

What routes can Mupirocin be administered by?

Accepted Answer

Available routes: Topical.

Question 3

Which species have cited Mupirocin dosing data?

Accepted Answer

Mupirocin dosing in the ExoticRx formulary covers 2 species: Cat (Domestic), Dog (Domestic).

Question 4

Is Mupirocin a controlled substance?

Accepted Answer

Mupirocin is not federally scheduled as a controlled substance, but is veterinary prescription only in most jurisdictions.

Question 5

What are the warnings or contraindications for Mupirocin?

Accepted Answer

Excellent anti-staphylococcal activity including some MRSP. Polyethylene glycol base — avoid on large open wounds (PEG absorption and nephrotoxicity). Do not use with other topicals.

Question 6

What are the side effects of Mupirocin?

Accepted Answer

Excellent anti-staphylococcal activity including some MRSP. Polyethylene glycol base — avoid on large open wounds (PEG absorption and nephrotoxicity). Do not use with other topicals.

Question 7

How does Mupirocin work?

Accepted Answer

Inhibits bacterial isoleucyl-tRNA synthetase, blocking protein synthesis. Bactericidal at concentrations achieved topically.

Species	Route	Dose	Frequency	Evidence	Source
Dog (Domestic)	Topical	0 mg/kg	q12h	Strong	Plumb's Veterinary Drug Handbook, 9th Ed
Dog (Domestic)	Topical	0 apply thin layer	q8-12h	Moderate	Plumb's Veterinary Drug Handbook, 9th Ed

Mupirocin

Drug Class

Routes

Indications

Mechanism of Action

Side effects & warnings

Species with Mupirocin dosing data (3 dose rules)

Evidence levels across 3 dose rules

Backed by a published primary source

Sample dosing (2 of 3 cited rules)

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