Monepantel for Sheep
Monepantel is used in sheep for GI nematodes including multi-drug resistant strains, GI nematodes including resistant strains, Multi-drug resistant nematodes (investigational). Routes documented in sheep: PO. ExoticRx tracks Monepantel dosing for sheep from primary veterinary literature; sign in to view the full rule set. Verify against current literature before clinical use.
Trade names: Zolvix
Dose rules — sign in to view
Cited dose rules for Monepantel in sheep are available with a free ExoticRx account. Each row carries the route, dose range, frequency, indication, evidence level, and primary-source citation.
Mechanism of action
Agonist of nematode-specific acetylcholine receptor (MPHCO-1), causing spastic paralysis. No cross-resistance with existing anthelmintic classes.
Side effects & warnings
Primarily for ruminants but investigational in companion animals. Novel resistance class. Do not use in food-producing animals in some jurisdictions.
Species-specific contraindications and adverse-reaction reports for sheep may differ from canine / feline reference data — consult the primary citations listed with each rule.
Why a species-specific page? Monepantel pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in sheep — the rules above are the citations specific to this species, not generic recommendations.
Sourced from primary literature; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.