ExoticRx · exoticrx.com/drugs/lithium-carbonate
Lithobid, Eskalith
Alters sodium transport in nerve and muscle cells. Modulates inositol phosphate and glycogen synthase kinase-3 signaling. Exact mood-stabilizing mechanism unclear.
Extremely narrow therapeutic index. Requires serum lithium monitoring. Nephrotoxic and thyrotoxic with chronic use. Ensure adequate sodium intake and hydration. Highly toxic in birds.
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Free-tier preview — dog and cat dosing. Pro and Student unlock all 2 species including reptiles, birds, pocket pets, livestock, and equine.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | PO | 10–20 mg/kg | q12h | Weak | Crowell-Davis SL, Veterinary Psychopharmacology, 2nd Ed |
| Cat (Domestic) | PO | 5–10 mg/kg | q12h | Anecdotal | Plumb's Veterinary Drug Handbook, 9th Ed |
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