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Fidaxomicin

Dificid

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Sourced from primary literature. Awaiting credentialed clinical reviewer — our editorial process.

Drug Class

Antibiotic

Routes

PO

Indications

Clostridioides difficile colitis

Mechanism of Action

Inhibits bacterial RNA polymerase at a distinct site from rifamycins. Narrow spectrum, primarily active against Clostridioides.

Side effects & warnings

Minimal systemic absorption. GI effects possible. Very limited veterinary data — use extrapolated from human medicine.

Species with Fidaxomicin dosing data (2 dose rules)

Cat (Domestic)Dog (Domestic)

Evidence levels across 2 dose rules

Weak×2

Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.

Backed by a published primary source

  • · Plumb's Veterinary Drug Handbook, 9th Ed

Sample dosing (2 of 2 cited rules)

Free-tier preview — dog and cat dosing. Pro and Student unlock all 2 species including reptiles, birds, pocket pets, livestock, and equine.

SpeciesRouteDoseFrequencyEvidenceSource
Dog (Domestic)PO5–10 mg/kgq12hWeakPlumb's Veterinary Drug Handbook, 9th Ed
Cat (Domestic)PO5–10 mg/kgq12hWeakPlumb's Veterinary Drug Handbook, 9th Ed

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