ExoticRx · exoticrx.com/drugs/ezogabine
Potiga
First potassium channel opener anticonvulsant. Activates KCNQ2/3 (Kv7.2/7.3) potassium channels, stabilizing resting membrane potential and reducing neuronal excitability.
Retinal pigment changes and skin discoloration with chronic use. Urinary retention. Withdrawn from human market but available for veterinary investigational use. Limited data.
Controlled substance
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
Free-tier preview — dog and cat dosing. Pro and Student unlock all 2 species including reptiles, birds, pocket pets, livestock, and equine.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | PO | 2–5 mg/kg | q8h | Anecdotal | Plumb's Veterinary Drug Handbook, 9th Ed |
| Cat (Domestic) | PO | 1–3 mg/kg | q8h-q12h | Anecdotal | Plumb's Veterinary Drug Handbook, 9th Ed |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.