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Esafoxolaner-Eprinomectin-Praziquantel

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Sourced from primary literature. Awaiting credentialed clinical reviewer — our editorial process.

Drug Class

Antiparasitic

Routes

TOPICAL

Indications

Fleasheartwormhookwormsroundwormstapewormsticks

Mechanism of Action

Esafoxolaner (isoxazoline) for ectoparasites; eprinomectin (avermectin) for nematodes and heartworm; praziquantel for cestodes. Broadest spectrum feline parasite product.

Side effects & warnings

Cats only. Monthly topical. First all-in-one product covering fleas, ticks, heartworm, roundworms, hookworms, and tapeworms in cats. Do not use in kittens <8 weeks.

Species with Esafoxolaner-Eprinomectin-Praziquantel dosing data (1 dose rule)

Cat (Domestic)

Evidence levels across 1 dose rule

Strong×1

Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.

Backed by a published primary source

  • · Plumb's Veterinary Drug Handbook, 9th Ed

Sample dosing (1 of 1 cited rule)

Free-tier preview — dog and cat dosing. Pro and Student unlock all 1 species including reptiles, birds, pocket pets, livestock, and equine.

SpeciesRouteDoseFrequencyEvidenceSource
Cat (Domestic)TOPICAL0 weight-based pipetteq30 daysStrongPlumb's Veterinary Drug Handbook, 9th Ed

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