Question 1

What is Enrofloxacin used for?

Accepted Answer

Enrofloxacin is indicated for: Bacterial infections, Bacterial infections (pneumonia, abscess), Bacterial infections (respiratory, GI), Bacterial infections (respiratory, UTI), Bacterial infections (skin, UTI, respiratory), Bacterial respiratory, Bovine respiratory disease, chronic respiratory, Complicated UTI, E. coli, Gram-negative enteritis, Mycoplasma haemofelis, Mycoplasma respiratory (acute), Osteomyelitis, Otitis media/interna, Pasteurella, Pasteurella multocida, Pneumonia (community-acquired), Prostatitis, pyelonephritis, respiratory, Respiratory infections (Bordetella, Streptococcus), Severe systemic infections, skin, snuffles, Streptococcus equi subsp. zooepidemicus, Susceptible bacterial infections, Swine respiratory disease.

Question 2

What routes can Enrofloxacin be administered by?

Accepted Answer

Available routes: PO, IM, SC, IV.

Question 3

Which species have cited Enrofloxacin dosing data?

Accepted Answer

Enrofloxacin dosing in the ExoticRx formulary covers 16 species: African Grey Parrot, African Pygmy Hedgehog, Ball Python, Bearded Dragon, Cat (Domestic), Cattle (Beef/Dairy), Chicken (Poultry), Chinchilla, Dog (Domestic), Ferret, Guinea Pig, Horse (Equine), Pet Rat, Rabbit (Domestic), Swine (Pig), Turkey.

Question 4

Is Enrofloxacin a controlled substance?

Accepted Answer

Enrofloxacin is not federally scheduled as a controlled substance, but is veterinary prescription only in most jurisdictions.

Question 5

What are the warnings or contraindications for Enrofloxacin?

Accepted Answer

Avoid in growing animals (cartilage damage). Do NOT use in cats at doses >5mg/kg (retinal toxicity). Avoid concurrent use with theophylline.

Question 6

What are the side effects of Enrofloxacin?

Accepted Answer

Avoid in growing animals (cartilage damage). Do NOT use in cats at doses >5mg/kg (retinal toxicity). Avoid concurrent use with theophylline.

Question 7

How does Enrofloxacin work?

Accepted Answer

Inhibits bacterial DNA gyrase and topoisomerase IV, preventing DNA replication and transcription.

Species	Route	Dose	Frequency	Evidence	Source
Dog (Domestic)	IM	5–10 mg/kg	q24h	Strong	Plumb's Veterinary Drug Handbook, 9th Ed
Dog (Domestic)	IM	5–10 mg/kg	q24h	Strong	Plumb's Veterinary Drug Handbook, 9th Ed

Enrofloxacin

Drug Class

Routes

Indications

Mechanism of Action

Side effects & warnings

Species with Enrofloxacin dosing data (80 dose rules)

Evidence levels across 80 dose rules

Backed by 9 published primary sources

Sample dosing (2 of 80 cited rules)

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Other formulations of Enrofloxacin