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Emodepside

Profender(combination)

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Sourced from primary literature. Awaiting credentialed clinical reviewer — our editorial process.

Drug Class

Antiparasitic

Routes

TOPICALPO

Indications

hookwormsRoundwormstapeworms

Mechanism of Action

Stimulates presynaptic secretin receptors (SLO-1 potassium channels) in nematodes, causing paralysis. Novel mechanism unrelated to other anthelmintics.

Side effects & warnings

Topical formulation for cats. Do not allow oral ingestion of topical product (salivation, vomiting). Novel anthelmintic class with activity against some resistant nematodes.

Species with Emodepside dosing data (1 dose rule)

Evidence levels across 1 dose rule

Strong×1

Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.

Backed by a published primary source

  • · Plumb's Veterinary Drug Handbook, 9th Ed

Sample dosing (1 of 1 cited rule)

Free-tier preview — dog and cat dosing. Pro and Student unlock all 1 species including reptiles, birds, pocket pets, livestock, and equine.

SpeciesRouteDoseFrequencyEvidenceSource
Cat (Domestic)TOPICAL3 mg/kgSingle applicationStrongPlumb's Veterinary Drug Handbook, 9th Ed

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Other formulations of Emodepside