ExoticRx · exoticrx.com/drugs/cefpodoxime-proxetil
Simplicef, Vantin
Oral third-generation cephalosporin prodrug. Inhibits bacterial cell wall synthesis with enhanced gram-negative spectrum.
Dogs only (FDA-approved). Convenient once-daily dosing. Well-tolerated. Good for skin infections, UTIs. Broader gram-negative coverage than first-generation cephalosporins.
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Free-tier preview — dog and cat dosing. Pro and Student unlock all 1 species including reptiles, birds, pocket pets, livestock, and equine.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | PO | 5–10 mg/kg | q24h | Strong | Plumb's Veterinary Drug Handbook, 9th Ed |
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