Question 1

What is Aztreonam used for?

Accepted Answer

Aztreonam is indicated for: Severe gram-negative infections.

Question 2

What routes can Aztreonam be administered by?

Accepted Answer

Available routes: IV, IM.

Question 3

Which species have cited Aztreonam dosing data?

Accepted Answer

Aztreonam dosing in the ExoticRx formulary covers 2 species: Cat (Domestic), Dog (Domestic).

Question 4

Is Aztreonam a controlled substance?

Accepted Answer

Aztreonam is not federally scheduled as a controlled substance, but is veterinary prescription only in most jurisdictions.

Question 5

What are the warnings or contraindications for Aztreonam?

Accepted Answer

No cross-reactivity with penicillin allergy in most cases. Limited veterinary data. Monitor renal function with prolonged use.

Question 6

What are the side effects of Aztreonam?

Accepted Answer

No cross-reactivity with penicillin allergy in most cases. Limited veterinary data. Monitor renal function with prolonged use.

Question 7

How does Aztreonam work?

Accepted Answer

Binds penicillin-binding protein 3 (PBP-3) of gram-negative bacteria, inhibiting cell wall synthesis. Active only against aerobic gram-negative organisms.

Species	Route	Dose	Frequency	Evidence	Source
Dog (Domestic)	IV	30–50 mg/kg	q8h	Weak	Plumb's Veterinary Drug Handbook, 9th Ed
Cat (Domestic)	IV	30–50 mg/kg	q8h	Weak	Plumb's Veterinary Drug Handbook, 9th Ed

Aztreonam

Drug Class

Routes

Indications

Mechanism of Action

Side effects & warnings

Species with Aztreonam dosing data (2 dose rules)

Evidence levels across 2 dose rules

Backed by a published primary source

Sample dosing (2 of 2 cited rules)

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