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Ampicillin for Swine

Ampicillin is used in swine for bacteremia, Bacterial infection, erysipelas, listeriosis. Routes documented in swine: PO, IV, IM, SC. ExoticRx tracks Ampicillin dosing for swine from primary veterinary literature; sign in to view the full rule set. Verify against current literature before clinical use.

Trade names: Polyflex

Dose rules — sign in to view

Cited dose rules for Ampicillin in swine are available with a free ExoticRx account. Each row carries the route, dose range, frequency, indication, evidence level, and primary-source citation.

Sources include: Carpenter's Exotic Animal Formulary, 6th Ed; Plumb's Veterinary Drug Handbook; Plumb's Veterinary Drug Handbook, 9th Ed

Mechanism of action

Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins. Broader spectrum than penicillin G with gram-negative coverage.

Side effects & warnings

CONTRAINDICATED in rabbits, guinea pigs, and hamsters (fatal dysbiosis). May cause GI upset. Cross-reactivity with other beta-lactams. IM injection may be painful.

Species-specific contraindications and adverse-reaction reports for swine may differ from canine / feline reference data — consult the primary citations listed with each rule.

Why a species-specific page? Ampicillin pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in swine — the rules above are the citations specific to this species, not generic recommendations.

Sourced from primary literature; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.