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Vitamin C (Ascorbic Acid)

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Sourced from primary literature. Awaiting credentialed clinical reviewer — our editorial process.

Drug Class

Supplement

Routes

POSCIV

Indications

Acute severe scurvyacute vitamin C deficiencyAntioxidantAntioxidant supplementationAntioxidant supplementation during illnesscopper hepatopathy adjunctFIC (feline idiopathic cystitis) adjunctNutritional supplementation during illnessnutritional supportPregnancy/lactation supplementation (increased requirement)Scurvy prevention during illnessScurvy prevention/treatmentSevere scurvyVitamin C supplementation (obligate requirement)

Mechanism of Action

Essential antioxidant and cofactor in collagen synthesis, immune function, and iron absorption. Guinea pigs cannot synthesize vitamin C endogenously (obligate requirement).

Side effects & warnings

ESSENTIAL supplement for guinea pigs (10-30 mg/kg/day minimum). Degrades rapidly in water — supplement daily. High parenteral doses may cause oxalate crystalluria. Most other species synthesize their own.

Species with Vitamin C (Ascorbic Acid) dosing data (25 dose rules)

Evidence levels across 25 dose rules

Weak×2Anecdotal×12Strong×7Extrapolated×2Moderate×2

Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.

Backed by 2 published primary sources

  • · Carpenter's Exotic Animal Formulary, 6th Ed
  • · Plumb's Veterinary Drug Handbook, 9th Ed

Sample dosing (2 of 25 cited rules)

Free-tier preview — dog and cat dosing. Pro and Student unlock all 7 species including reptiles, birds, pocket pets, livestock, and equine.

SpeciesRouteDoseFrequencyEvidenceSource
Dog (Domestic)PO10–30 mg/kgq12hWeakPlumb's Veterinary Drug Handbook, 9th Ed
Dog (Domestic)PO10–30 mg/kgq12hWeakPlumb's Veterinary Drug Handbook, 9th Ed

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