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Virginiamycin (Feed Additive) for Swine

Virginiamycin (Feed Additive) is used in swine for acidosis prevention, feed efficiency, Growth promotion, Liver abscess prevention. Routes documented in swine: PO. ExoticRx tracks Virginiamycin (Feed Additive) dosing for swine from primary veterinary literature; sign in to view the full rule set. Verify against current literature before clinical use.

Trade names: V-Max, Stafac

Dose rules — sign in to view

Cited dose rules for Virginiamycin (Feed Additive) in swine are available with a free ExoticRx account. Each row carries the route, dose range, frequency, indication, evidence level, and primary-source citation.

Sources include: FDA NADA Label

Mechanism of action

Streptogramin antibiotic that inhibits bacterial protein synthesis. Consists of two synergistic components (virginiamycin M1 and S1) that bind to the 50S ribosomal subunit.

Side effects & warnings

Feed additive use only. Used for growth promotion and prevention of liver abscesses in feedlot cattle. Cross-resistance with quinupristin-dalfopristin has raised public health concerns.

Species-specific contraindications and adverse-reaction reports for swine may differ from canine / feline reference data — consult the primary citations listed with each rule.

Why a species-specific page? Virginiamycin (Feed Additive) pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in swine — the rules above are the citations specific to this species, not generic recommendations.

Sourced from primary literature; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.