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Tylosin for Swine

Tylosin is used in swine for air sacculitis, arthritis, Bovine respiratory disease, Chronic colitis. Routes documented in swine: PO, IM. ExoticRx tracks Tylosin dosing for swine from primary veterinary literature; sign in to view the full rule set. Verify against current literature before clinical use.

Trade names: Tylan

Dose rules — sign in to view

Cited dose rules for Tylosin in swine are available with a free ExoticRx account. Each row carries the route, dose range, frequency, indication, evidence level, and primary-source citation.

Sources include: Carpenter's Exotic Animal Formulary, 6th Ed; FDA NADA Label; Plumb's Veterinary Drug Handbook, 9th Ed

Mechanism of action

Binds 50S ribosomal subunit, inhibiting bacterial protein synthesis. Anti-inflammatory properties in GI tract.

Side effects & warnings

CONTRAINDICATED in rabbits, guinea pigs (fatal dysbiosis). Commonly used for chronic colitis in dogs. Very bitter taste. IM injection painful.

Species-specific contraindications and adverse-reaction reports for swine may differ from canine / feline reference data — consult the primary citations listed with each rule.

Why a species-specific page? Tylosin pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in swine — the rules above are the citations specific to this species, not generic recommendations.

Sourced from primary literature; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.