ExoticRx · exoticrx.com/drugs/tiludronate
Tildren
Bisphosphonate that inhibits osteoclast-mediated bone resorption by binding to hydroxyapatite in bone. Does not impair bone mineralization.
FDA-approved for navicular disease in horses. IV infusion over 90 minutes. Transient colic, renal toxicity at high doses. Do not use in horses with renal disease.
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| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | IV | 0.1–0.3 mg/kg | IV infusion q28 days | Weak | Plumb's Veterinary Drug Handbook, 9th Ed |
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