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Progesterone for Cattle

Progesterone is used in cattle for Estrus synchronization, Estrus synchronization (CIDR), Luteal insufficiency, out-of-season breeding. Routes documented in cattle: IM, Intravaginal. ExoticRx tracks Progesterone dosing for cattle from primary veterinary literature; sign in to view the full rule set. Verify against current literature before clinical use.

Trade names: various generic

Dose rules — sign in to view

Cited dose rules for Progesterone in cattle are available with a free ExoticRx account. Each row carries the route, dose range, frequency, indication, evidence level, and primary-source citation.

Sources include: FDA NADA Label; Merck Veterinary Manual; Plumb's Veterinary Drug Handbook, 9th Ed

Mechanism of action

Natural progestin binding progesterone receptors. Maintains pregnancy, suppresses estrus, and has anti-inflammatory effects on endometrium.

Side effects & warnings

Used for luteal insufficiency and pregnancy maintenance. Exogenous progestins can cause pyometra, mammary neoplasia, diabetes, and acromegaly with prolonged use.

Species-specific contraindications and adverse-reaction reports for cattle may differ from canine / feline reference data — consult the primary citations listed with each rule.

Why a species-specific page? Progesterone pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cattle — the rules above are the citations specific to this species, not generic recommendations.

Sourced from primary literature; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.