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Probiotics (Saccharomyces boulardii)

Florastor, Mycequin

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Sourced from primary literature. Awaiting credentialed clinical reviewer — our editorial process.

Drug Class

Supplement

Routes

PO

Indications

Acute and antibiotic-associated diarrheaGI dysbiosis/Antibiotic-associated diarrhea

Mechanism of Action

Non-colonizing probiotic yeast that produces proteases degrading C. difficile toxins, stimulates secretory IgA, and enhances brush border enzyme activity.

Side effects & warnings

Do not use in severely immunocompromised or critically ill patients (fungemia risk). Not destroyed by antibiotics (unlike bacterial probiotics). Store at room temperature.

Species with Probiotics (Saccharomyces boulardii) dosing data (2 dose rules)

Cat (Domestic)Dog (Domestic)

Evidence levels across 2 dose rules

Moderate×2

Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.

Backed by 2 published primary sources

  • · JVIM Probiotic Meta-analysis; Plumb's 9th Ed
  • · JVIM Probiotic Reviews

Sample dosing (2 of 2 cited rules)

Free-tier preview — dog and cat dosing. Pro and Student unlock all 2 species including reptiles, birds, pocket pets, livestock, and equine.

SpeciesRouteDoseFrequencyEvidenceSource
Dog (Domestic)PO5–20 mg/kgq12-24hModerateJVIM Probiotic Meta-analysis; Plumb's 9th Ed
Cat (Domestic)PO5–15 mg/kgq12-24hModerateJVIM Probiotic Reviews

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