ExoticRx · exoticrx.com/drugs/polysulfated-glycosaminoglycan
Adequan Canine, Adequan Equine
Inhibits catabolic enzymes (metalloproteinases, serine proteases) in cartilage. Stimulates proteoglycan and hyaluronic acid synthesis. Anti-inflammatory in joints.
FDA-approved for dogs and horses. IM injection series (usually 8 doses over 4 weeks). May affect coagulation — avoid in patients on anticoagulants. Injection site reactions.
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Free-tier preview — dog and cat dosing. Pro and Student unlock all 1 species including reptiles, birds, pocket pets, livestock, and equine.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | IM | 4.4 mg/kg | q3-5 days x 8 injections | Strong | Plumb's Veterinary Drug Handbook, 9th Ed |
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