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Pirlimycin (Intramammary) for Cattle

Pirlimycin (Intramammary) is used in cattle for Clinical and subclinical mastitis, Clinical mastitis (gram-positive). Routes documented in cattle: Intramammary. ExoticRx tracks Pirlimycin (Intramammary) dosing for cattle from primary veterinary literature; sign in to view the full rule set. Verify against current literature before clinical use.

Trade names: Pirsue

Dose rules — sign in to view

Cited dose rules for Pirlimycin (Intramammary) in cattle are available with a free ExoticRx account. Each row carries the route, dose range, frequency, indication, evidence level, and primary-source citation.

Sources include: FDA NADA Label

Mechanism of action

Lincosamide antibiotic that inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit. Formulated specifically for intramammary infusion.

Side effects & warnings

For treatment of clinical and subclinical mastitis in lactating dairy cattle caused by susceptible staphylococci and streptococci. Observe milk withdrawal period (36 hours). Not for systemic use.

Species-specific contraindications and adverse-reaction reports for cattle may differ from canine / feline reference data — consult the primary citations listed with each rule.

Why a species-specific page? Pirlimycin (Intramammary) pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cattle — the rules above are the citations specific to this species, not generic recommendations.

Sourced from primary literature; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.