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Melengestrol Acetate for Cattle

Melengestrol Acetate is used in cattle for Estrus suppression, Estrus suppression in feedlot heifers, synchronization. Routes documented in cattle: PO. ExoticRx tracks Melengestrol Acetate dosing for cattle from primary veterinary literature; sign in to view the full rule set. Verify against current literature before clinical use.

Trade names: MGA

Dose rules — sign in to view

Cited dose rules for Melengestrol Acetate in cattle are available with a free ExoticRx account. Each row carries the route, dose range, frequency, indication, evidence level, and primary-source citation.

Sources include: FDA NADA Label

Mechanism of action

Synthetic progestogen that suppresses estrus and ovulation in heifers by negative feedback on gonadotropin secretion. Also has mild growth-promoting effects.

Side effects & warnings

For heifers only. Do not use in dairy cows or breeding animals. Used in estrus synchronization protocols (MGA + prostaglandin). No withdrawal period for meat at approved doses. Not for use in animals intended for breeding during treatment.

Species-specific contraindications and adverse-reaction reports for cattle may differ from canine / feline reference data — consult the primary citations listed with each rule.

Why a species-specific page? Melengestrol Acetate pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cattle — the rules above are the citations specific to this species, not generic recommendations.

Sourced from primary literature; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.