Question 1

What is Lokivetmab Injectable used for?

Accepted Answer

Lokivetmab Injectable is indicated for: Atopic dermatitis, Atopic dermatitis (pruritus control), Off-label pruritus control.

Question 2

What routes can Lokivetmab Injectable be administered by?

Accepted Answer

Available routes: SC.

Question 3

Which species have cited Lokivetmab Injectable dosing data?

Accepted Answer

Lokivetmab Injectable dosing in the ExoticRx formulary covers 2 species: Cat (Domestic), Dog (Domestic).

Question 4

Is Lokivetmab Injectable a controlled substance?

Accepted Answer

Lokivetmab Injectable is not federally scheduled as a controlled substance, but is veterinary prescription only in most jurisdictions.

Question 5

What are the warnings or contraindications for Lokivetmab Injectable?

Accepted Answer

Dogs only (species-specific). Vomiting may occur post-injection. Avoid in breeding/pregnant/lactating dogs. Efficacy lasts ~4-8 weeks. No known drug interactions.

Question 6

What are the side effects of Lokivetmab Injectable?

Accepted Answer

Dogs only (species-specific). Vomiting may occur post-injection. Avoid in breeding/pregnant/lactating dogs. Efficacy lasts ~4-8 weeks. No known drug interactions.

Question 7

How does Lokivetmab Injectable work?

Accepted Answer

Caninized monoclonal antibody targeting interleukin-31 (IL-31), a key pruritogenic cytokine. Neutralizes IL-31 before it can bind to its receptor on sensory neurons.

Species	Route	Dose	Frequency	Evidence	Source
Dog (Domestic)	SC	1–2 mg/kg	q4-8 weeks	Strong	Plumb's Veterinary Drug Handbook, 9th Ed
Dog (Domestic)	SC	1–2 mg/kg	q4-8 weeks	Strong	Plumb's Veterinary Drug Handbook, 9th Ed

Lokivetmab Injectable

Drug Class

Routes

Indications

Mechanism of Action

Side effects & warnings

Species with Lokivetmab Injectable dosing data (3 dose rules)

Evidence levels across 3 dose rules

Backed by a published primary source

Sample dosing (2 of 3 cited rules)

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Other formulations of Lokivetmab