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Lincomycin-Spectinomycin for Swine

Lincomycin-Spectinomycin is used in swine for Air sacculitis, bacterial arthritis, CRD complex, E. coli. Routes documented in swine: PO, IM, Water. ExoticRx tracks Lincomycin-Spectinomycin dosing for swine from primary veterinary literature; sign in to view the full rule set. Verify against current literature before clinical use.

Trade names: Linco-Spectin, LS-50

Dose rules — sign in to view

Cited dose rules for Lincomycin-Spectinomycin in swine are available with a free ExoticRx account. Each row carries the route, dose range, frequency, indication, evidence level, and primary-source citation.

Sources include: FDA NADA Label; Merck Veterinary Manual

Mechanism of action

Synergistic combination of lincomycin (50S ribosomal subunit inhibitor) and spectinomycin (30S ribosomal subunit inhibitor). Provides enhanced gram-positive and Mycoplasma coverage.

Side effects & warnings

For swine and poultry only. Fatal if given to horses or ruminants. Observe meat withdrawal periods.

Species-specific contraindications and adverse-reaction reports for swine may differ from canine / feline reference data — consult the primary citations listed with each rule.

Why a species-specific page? Lincomycin-Spectinomycin pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in swine — the rules above are the citations specific to this species, not generic recommendations.

Sourced from primary literature; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.