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Ivermectin for Swine

Ivermectin is used in swine for bots, Cheyletiella (fur mites), demodicosis, Ear mites. Routes documented in swine: PO, SC, TOPICAL. ExoticRx tracks Ivermectin dosing for swine from primary veterinary literature; sign in to view the full rule set. Verify against current literature before clinical use.

Trade names: Ivomec, Heartgard

Dose rules — sign in to view

Cited dose rules for Ivermectin in swine are available with a free ExoticRx account. Each row carries the route, dose range, frequency, indication, evidence level, and primary-source citation.

Sources include: Carpenter's Exotic Animal Formulary, 6th Ed; ExoticRx 2026 (chinchilla dosing guide); Carpenter 6e; ExoticRx 2026 (ferret dosing guide); Carpenter 6e; …

Mechanism of action

Potentiates glutamate-gated chloride channels in invertebrate nerve and muscle cells, causing paralysis and death of parasites.

Side effects & warnings

TOXIC to MDR1-mutant dogs (Collies, Shelties, Aussies) at elevated doses. DO NOT use in chelonians (turtles/tortoises). Narrow safety margin in some species. Test MDR1 status before use in herding breeds.

Species-specific contraindications and adverse-reaction reports for swine may differ from canine / feline reference data — consult the primary citations listed with each rule.

Why a species-specific page? Ivermectin pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in swine — the rules above are the citations specific to this species, not generic recommendations.

Sourced from primary literature; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.